| Name | Meaning | Gender | Origin |
| Bear | Large mammal with large head, bulky body and coarse thick fur | Unisex | English |
| Boomer | A large full grown kangaroo. A baby boomer. | Unisex | English |
| Bruiser | A large heavyset man | Unisex | English |
| Bull | The adult male of certain large animals like cattle and elephants | Unisex | English |
| Cherokee | People Of A Different Speech. One Of The Largest American Indian Tribes. | Unisex | English |
| Cougar | A large powerful American mountain cat | Unisex | English |
| Gordon | Large fort | Male | English |
| Gordy | Large fort | Male | English |
| Jaguar | Large Spotted Feline | Male | English |
| Magnum | A large type of wine bottle. | Unisex | English |
| Maier | Farmer; bright, shining; larger | Male | English |
| Moose | Largest member of the deer family. Moose have heavy brown bodies with humped shoulders and broad antlers. | Unisex | English |
| Pumpkin | Large round fruit with orange skin | Unisex | English |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Sequoia | Large Tree | Female | Native American |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Treva | Large settlement | Female | Welsh |
| Trevor | Large settlement | Male | Welsh |