| Name | Meaning | Gender | Origin |
|---|
| Slim | Slender in proportion to height. | Unisex | English |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Unisex | English |
| Snuggles | To curl up closely, cuddle | Unisex | English |
| Sol | Peace | Male | Hebrew |
| Sparky | Animated, lively. | Unisex | English |
| Spice | Plant used to flavour food or beverages. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Sprout | | Unisex | Hebrew |
| Squirt | Slang for a small person | Unisex | English |
| Stanley | Meadow that is stony | Male | English |
| Stumpy | A short, thickset person | Unisex | English |
| Suede | Swedish | Unisex | English |
| Sunny | Filled with sunlight | Male | English |
| Sweetie | Sweetheart. | Unisex | English |
| Tango | | Unisex | Hebrew |
| T-bone | A thick steak containing a T shaped bone. | Unisex | English |
| Teddy | Gift of God | Male | Greek |
| Tex | Of Texas | Unisex | English |
| Timmy | To honor God, to fear God | Male | Greek |
| Titus | Of The Giants | Male | Latin |
| Toby | God is good | Unisex | Hebrew |
| Tootsie | A girl or young woman. | Unisex | English |
| Tory | Conqueror | Unisex | Latin |
| Tucker | Someone who folds cloth | Male | English |
| Twiggy | | Unisex | Hebrew |
| Tyler | Tile maker | Male | English |
| Vern | Place of alders | Male | Norse |
| Watson | Son of Walter | Male | English |
| Wilbur | Will | Male | English |