| Name | Meaning | Gender | Origin |
|---|
| Samantha | Listener | Female | Aramaic |
| Sammy | His name is God | Unisex | Hebrew |
| Samson | Sun | Male | Hebrew |
| Sandy | Defending men | Male | Greek |
| Sassy | Lively and spirited | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Satin | Amber | Female | Armenian |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Scarlet | Scarlet | Female | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Shark | | Unisex | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Sherbert | Frozen dessert made from fruit, sugar and water. Australian slang for beer. | Unisex | English |
| Sherlock | With cropped hair | Male | English |
| Silver | Silver (the metal or colour) | Male | English |
| Slate | | Unisex | Hebrew |
| Snuffles | | Unisex | Hebrew |
| Sol | Peace | Male | Hebrew |
| Sophie | Wisdom | Female | Greek |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Star | Star | Female | Latin |
| Stone | Stone | Male | English |
| Storm | Violent weather | Female | English |
| Talon | A claw | Male | English |
| Tania | Abbreviation Of Tatiana Which Is Feminine Of The Roman Family Clan Name Tatius. | Female | Latin |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tara | Crag | Female | Gaelic |
| Tempest | Storm | Female | English |
| Tex | Of Texas | Unisex | English |