| Name | Meaning | Gender | Origin |
|---|
| Rufus | Red | Male | Latin |
| Sadie | Princess | Female | Hebrew |
| Salome | Tranquil | Female | English |
| Scarlett | Scarlet | Female | English |
| Sexy | | Unisex | Hebrew |
| Sheba | Daughter of an oath | Female | Hebrew |
| Skeeter | | Unisex | Hebrew |
| Skittles | | Unisex | Hebrew |
| Sniper | A skilled shooter who spots targets from a concealed place. | Unisex | English |
| Sora | Sky | Female | Japanese |
| Spanky | | Unisex | Hebrew |
| Sparky | Animated, lively. | Unisex | English |
| Spaz | For a spazy kitty | Unisex | English |
| Speedy | Rapid motion, swift. | Unisex | English |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Unisex | English |
| Spunky | Spirited, plucky. | Unisex | English |
| Stephanie | Crowned In Victory | Female | English |
| Sticky | | Unisex | Hebrew |
| Storm | Violent weather | Female | English |
| Tallulah | Abundance, lady, princess | Female | Gaelic |
| Tarzan | White skin | Unisex | Literary |
| Taz | Wild Animal, Thrid Born | Unisex | American |
| Tempest | Storm | Female | English |
| Thumper | To walk with heavy steps | Unisex | English |
| Tiger | Tiger | Unisex | English |
| Trixie | Voyager through life | Female | Latin |
| Trouble | A cause of disturbance or difficulty. | Unisex | English |
| Troy | Troyes | Female | French |
| Turbo | Driven by a turbine - turbocharged | Unisex | English |
| Tyson | Son of Dye | Male | English |