| Name | Meaning | Gender | Origin |
|---|
| Sasha | Defending men | Unisex | Greek |
| Satin | Amber | Female | Armenian |
| Scarlet | Scarlet | Female | English |
| Scout | Observer | Unisex | American English |
| Shadow | Shadow | Unisex | English |
| Sheba | Daughter of an oath | Female | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Shiloh | Gift for him | Unisex | Hebrew |
| Shiva | Auspicious | Unisex | Sanskrit |
| Shona | God is gracious | Female | Hebrew |
| Simba | Lion | Female | Swahili |
| Skipper | Master of a Ship | Male | American English |
| Sky | Sky | Unisex | Norse |
| Skyler | Guarded | Unisex | Dutch |
| Sly | A forest | Unisex | Latin |
| Sniper | A skilled shooter who spots targets from a concealed place. | Unisex | English |
| Sophie | Wisdom | Female | Greek |
| Sparky | Animated, lively. | Unisex | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Stormy | Violent weather | Unisex | English |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sullivan | Keen eye | Male | Gaelic |
| Sushi | Raw fish. | Unisex | English |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tasha | (Christ's) birthday | Female | Latin |
| Taurus | Bull | Unisex | Latin |
| T-bone | A thick steak containing a T shaped bone. | Unisex | English |
| Teddy | Gift of God | Male | Greek |
| Thor | Thunder | Male | Norse |
| Thunder | Stormy Tempered | Unisex | English |