| Name | Meaning | Gender | Origin |
| Sasha | Defending men | Unisex | Greek |
| Sasquatch | Has extra toes and hence is a bigfoot | Unisex | English |
| Satan | The Devil and adversary of God | Unisex | English |
| Satin | Amber | Female | Armenian |
| Saturn | Sixth and second largest planet away from the Sun. | Unisex | English |
| Savannah | Plateau | Female | Spanish |
| Scarlet | Scarlet | Female | English |
| Scout | Observer | Unisex | American English |
| Shark | | Unisex | Hebrew |
| Sharona | The plains | Female | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Shiloh | Gift for him | Unisex | Hebrew |
| Sierra | Mountain range | Female | Spanish |
| Snickers | A brand of candy bar. | Unisex | English |
| Sophie | Wisdom | Female | Greek |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Taryn | King Of Rocky Hill. Variant Of Tarynn. | Female | American English |
| Tasha | (Christ's) birthday | Female | Latin |
| Tempest | Storm | Female | English |
| Tex | Of Texas | Unisex | English |
| Thunder | Stormy Tempered | Unisex | English |
| Tilly | Powerful battler | Unisex | Germanic |
| Titan | Powerful big man | Unisex | Greek |
| Trojan | | Unisex | Hebrew |
| Trooper | A state or mounted police officer. Also a member of a cavalry unit. | Unisex | English |
| Trouble | A cause of disturbance or difficulty. | Unisex | English |
| Velvet | Soft | Female | English |
| Vesta | Guardian Of The Sacred Fire | Female | Latin |
| Wanda | Wanderer | Female | Slavonic |