| Name | Meaning | Gender | Origin |
|---|
| Scooby | | Unisex | Hebrew |
| Scooter | One who goes suddenly and speedily. | Unisex | English |
| Scout | Observer | Unisex | American English |
| Sexy | | Unisex | Hebrew |
| Shadow | Shadow | Unisex | English |
| Shamus | Supplanter | Male | Hebrew |
| Shelby | A place where willows grow | Female | American English |
| Sierra | Mountain range | Female | Spanish |
| Simba | Lion | Female | Swahili |
| Skittles | | Unisex | Hebrew |
| Skye | Cloud | Male | Norse |
| Snickers | A brand of candy bar. | Unisex | English |
| Snoopy | | Unisex | Hebrew |
| Snowball | | Unisex | Hebrew |
| Sophie | Wisdom | Female | Greek |
| Sparkey | | Unisex | Hebrew |
| Sparky | Animated, lively. | Unisex | English |
| Spencer | Someone who gives out goods | Male | French |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | English |
| Stella | Star | Female | Latin |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | English |
| Sydney | Wide meadow | Female | English |
| Taco | A folded fried tortilla filled with meat, cheese and spices. | Unisex | English |
| Talia | Dew of God | Female | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | English |
| Tasha | (Christ's) birthday | Female | Latin |
| Tate | "Pleasant And Bright."Some Variants Are Tait, Taite, And Tayte. | Female | English |
| Teddy | Gift of God | Male | Greek |
| Tessa | Harvester | Female | Greek |
| Thor | Thunder | Male | Norse |